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Advanced Topics in Forensic DNA Typing: Methodology


Author: John Butler

Publisher: Academic Press

Publish Date: 21st July 2011

ISBN-13: 9780123878236

Pages: 704

Language: English



Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler’s internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience.  This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues.

Table of Contents

Dedication Foreword Introduction Acknowledgments About the Author Chapter 1. Sample Collection, Storage, and Characterization Chapter 2. DNA Extraction Methods Chapter 3. DNA Quantitation Chapter 4. PCR Amplification Chapter 5. Short Tandem Repeat (STR) Loci and Kits Chapter 6. Capillary Electrophoresis Chapter 7. Quality Assurance and Validation Chapter 8. DNA Databases Chapter 9. Missing Persons and Disaster Victim Identification Efforts Chapter 10. Degraded DNA Chapter 11. Low-Level DNA Testing Chapter 12. Single Nucleotide Polymorphisms and Applications Chapter 13. Y-Chromosome DNA Testing Chapter 14. Mitochondrial DNA Analysis Chapter 15. X-Chromosome Analysis Chapter 16. Non-human DNA Chapter 17. New Technologies and Automation Chapter 18. Legal Aspects of DNA Testing and the Scientific Expert in Court Appendix 1. Reported Sizes and Sequences of STR Alleles Appendix 2. Familial DNA Searches: Potential, Pitfalls, and Privacy Concerns Appendix 3. List of Suppliers for DNA Instruments, Reagents, Services Appendix 4. Interviews Supporting Legal Aspects of DNA Testing Subject Index